The structure of the Procedural System of the CRC is based on different kinds of standard functional documents:

• Master Documents: a reference document which contains the definition and the administration of the life-cycle of the functional documents which constitute the structure of the Procedural System created to support the CRC organization. Furthermore the Master Document is to be applied to the management of Quality registrations (documents, forms in compliance with the law in force or to define the application of procedures and the documents for the management of the Quality System).
• Policies (POL): high level documents in which the CRC Management outlines the principles to be followed in order to define, improve and manage the main business processes, according to the CRC Mission and following the values characterizing the CRC Management.
• General Procedures (PG): documents supporting an effective and efficient functioning of the cross-functional organizational processes.
• Standard Operating Procedures (SOP): documents which aim to describe in detail specific processes or activities which are generally carried out or pertain to a single function. A full set of SOPs is available for on-site review and an updated list with all SOP titles will be provided on request.
• Recording documents: documents which formalize rationales, summaries decisions in structured systems in order to guarantee a proper level of documentation, sharing best practices and knowledge management.

QA activities for CRC are performed by an external consultant. An activity plan is set up annually and it usually includes at least 1 CRC Facility Audit and the review of procedural documents. Facility audits have been carried out every year by a QA expert. Audits were performed by some Sponsors.